Category: Acetylcholine ??7 Nicotinic Receptors

  • Recent clinical trials have shown that ivabradine (IVA), a drug that

    Recent clinical trials have shown that ivabradine (IVA), a drug that inhibits the funny current (those more negative than the spontaneous diastolic depolarization (DD) between action potentials (APs). (~?60 mV) amplitude was only ?2.90.4 pA/pF, and was reduced by only 416% by IVA. Thus, amplitude and its inhibition by IVA at physiologically relevant membrane potentials…