Category: GlyR

  • Lack of function of Bruton’s tyrosine kinase (Btk) causes X-linked agammaglobulinemia

    Lack of function of Bruton’s tyrosine kinase (Btk) causes X-linked agammaglobulinemia (XLA) in humans and X-linked immunodeficiency in mice (xid). phosphorylation or a negative charge Bosutinib at this site may down-regulate the function of Btk by selectively suppressing the B cell calcium signaling pathway. Immunoreceptors, including the B cell receptor (BCR), transduce cell surface stimulations…