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Groucho (Gro)/TLE transcriptional corepressors get excited about a number of developmental systems, including neuronal differentiation. BF-1-mediated transcriptional repression. In keeping with these observations, Grg6 inhibits the binding of Gro/TLE1 to BF-1 and will not repress transcription when geared to DNA. Furthermore, coexpression of Grg6 and BF-1 in cortical progenitor cells results in a reduction in…