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The cystic fibrosis transmembrane conductance regulator (CFTR) Cl? stations are constitutively turned on in perspiration ducts. endogenous phosphatase activity with okadaic acidity (10?8?M) within the permeabilization-induced deactivation of gCFTR. We display that okadaic acidity (1) inhibits an endogenous phosphatase in charge of dephosphorylating cAMP however, not cGMP or G protein-activated CFTR and (2) prevents deactivation…