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Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) have specific medical
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) have specific medical features but a common pathologycytoplasmic inclusions abundant with TDP43. and mutations in a number of genes trigger ALS, FTD, or both1. TDP43 is usually a nuclear RNA-binding proteins involved in many areas of RNA control3 that positively shuttles between your nucleus and cytoplasm4. In…