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Radioactive-iodine (RAI) therapy is normally unprevailing as anaplastic thyroid cancer (ATC) management, due to the reduction in the endogenous sodium iodide symporter (NIS) expression. Furthermore, we examined improvement of NIS promoter and healing efficiency of RAI in ATC tumour xenograft mice. After K905-0266 TKI treatment, the appearance of endogenous NIS was considerably elevated, while phosphorylated-ERK…