Discovery of novel inhibitors for the treatment of Cancer

Tag: CD44

  • Hypoxia-inducible factors 1 and 2 (HIF-1 and -2) control oxygen supply

    Hypoxia-inducible factors 1 and 2 (HIF-1 and -2) control oxygen supply to tissues by regulating erythropoiesis, angiogenesis and vascular homeostasis. cells (ECs) offer barrier, transport, artificial, and metabolic features at the user interface of bloodstream and adjacent cells, plus they play a central part in the organism’s response to hypoxia, because they regulate vascular shade,…

  • Calcific aortic stenosis (AS) is really a progressive disease without effective

    Calcific aortic stenosis (AS) is really a progressive disease without effective medical therapy that ultimately requires aortic valve replacement (AVR) for serious valve obstruction. AVR is currently available for sufferers with serious comorbidities, is preferred in sufferers who are considered inoperable and it is a reasonable option to operative AVR in risky sufferers. CD44 0.0001)…