Tag: Imatinib Mesylate enzyme inhibitor

Supplementary Materialsoncotarget-09-37549-s001. the telomere duration at which turmoil was initiated, but affected fix of eroded telomeres, leading to an elevated in intra-chromosomal telomere fusion. This was accompanied by enhanced DNA damage checkpoint activation and elevated levels of apoptosis. We propose that PARP inhibitors impair the restoration of dysfunctional telomeres and/or induce replicative stress at telomeres…