Tag: Muc1
-
The cystic fibrosis transmembrane conductance regulator (CFTR) Cl? stations are constitutively
The cystic fibrosis transmembrane conductance regulator (CFTR) Cl? stations are constitutively turned on in perspiration ducts. endogenous phosphatase activity with okadaic acidity (10?8?M) within the permeabilization-induced deactivation of gCFTR. We display that okadaic acidity (1) inhibits an endogenous phosphatase in charge of dephosphorylating cAMP however, not cGMP or G protein-activated CFTR and (2) prevents deactivation…