Tag: Olaparib ic50

Supplementary Materials1. subcellular distribution of mitochondria in breast cancer cells. For example, silencing Drp1 or overexpression of Mfn1 inhibited lamellipodia formation, a key step for malignancy metastasis, and suppressed chemoattractant-induced recruitment of mitochondria to lamellipodial areas. Conversely, silencing Mfn proteins resulted in more cell distributing and lamellipodia formation, causing build up of more mitochondria in…