Tag: order SCR7

Avoidance of apoptosis is a key mechanism that malignancies, including acute leukemias and MDS, utilize in order to proliferate and resist chemotherapy. to exhibit high potency inhibition of BCL-2, BCL-XL, and BCL-W, with greater affinity binding of these proteins by two to three orders of magnitude, order SCR7 compared to prior compounds (20). Notably, this…