Tag: Torcetrapib

-Synuclein is an integral pathogenic proteins that aggregates in hallmark lesions in Parkinson’s disease and other -synucleinopathies. these disorders. In PD, there is certainly increased TG2 proteins and mRNA appearance in the substantia nigra (10, 11) and elevated TG2 protein amounts in the cerebrospinal liquid (12). Furthermore, the isopeptide bonds produced by TG2 colocalize with…